J Bone Metab. 2023 Aug; 30(3): 231–244. Published online 2023 Aug 31. doi: 10.11005/jbm.2023.30.3.231
Dental pulp stem cells (DPSCs) have garnered significant interest in dental research for their unique characteristics and potential in tooth development and regeneration. While there were many studies to define their stem cell-like characteristics and osteogenic differentiation functions that are considered ideal candidates for regenerating damaged dental pulp tissue, how endogenous DPSCs respond to dental pulp injury and supply new dentin-forming cells has not been extensively investigated in vivo. Here, we review the recent progress in identity, function, and regulation of endogenous DPSCs and their clinical potential for pulp injury and regeneration. In addition, we discuss current advances in new mouse models, imaging techniques, and its practical uses and limitations in the analysis of DPSCs in pulp injury and regeneration in vivo.
Practice Question
Results
#1. The pulp stem cells are
Pulpal stem cells are pluripotent in nature. The stem cells are shown to undergo proliferation and migrate to the site of injured odontoblasts and produce dentin.